Search for articles

Article Detail

Diagnostic performance of international ovarian tumor analysis (IOTA) simple descriptors, simple rules and sassone scoring system among patients with ovarian disease in a tertiary specialty hospital

Ma. Teresita S. de Guia-Liwanag, MD, FPOGS and Angeline A. Gil-Armeza, MD, FPOGS, FPSUOG
Department of Obstetrics and Gynecology, Dr. Jose Fabella Memorial Hospital

Background: Accessibility, cost-effectiveness and consistency in identifying pelvic masses made ultrasonography one of the first imaging modality used by clinicians in evaluating women with ovarian disease. Scoring systems to differentiate a benign or malignant lesion has been formulated for many years and the International Ovarian Tumor Analysis (IOTA) group has developed several evidenced-based algorithms for classifying adnexal diseases. This research performs prospective validation using IOTA Simple Descriptors and IOTA Simple Rules, compared with Sassone scoring system to differentiate benign and malignant disease.

Objective: To determine and compare diagnostic performance of IOTA Simple descriptors, IOTA Simple rules and Sassone Scoring System in classifying benign and malignant masses.

Study Design: A cross-sectional study was done on patients assessed to have adnexal mass or tumors either by symptoms or by physical examination and confirmed by ultrasound using two-dimensional gray-scale with Doppler studies. The classification by sonographic features was based on the IOTA Simple Descriptors, IOTA Simple Rules and Sassone Scoring System and correlated with the histopathologic result as the gold standard.

Results: A total of eighty-two cases were analyzed in the study, seventy three of which was benign. Of those with malignancy, sixty one percent belonged to ages 31-50 years old. The most common benign histopathologic diagnoses were dermoid, endometrial cyst and serous cyst, while Adenocarcinoma is the most frequent type of ovarian carcinoma. The results showed high sensitivity for IOTA simple descriptors for benign tumors at 95%. On the other hand, specificity was 85% for both IOTA Simple Rule and Sassone scoring index with low sensitivity at 58% and 44% respectively.

Conclusion: Accuracy of the different sonologic indexes ranges from 72 to 83%. Comparing IOTA Simple Rules and Sassone Score, specificity was comparable at 85%, however with lower sensitivity for Sassone Score System.