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Effect of 2-week bedtime ingestion of apple cider vinegar on the blood glucose concentration (fasting blood sugar and second hour blood sugar) of gravidas with gestational diabetes mellitus in a tertiary hospital

Myra G. Casiple-Solas, MD and Maria Dolores A. Mercado, MD, FPOGS
Department of Obstetrics and Gynecology, Angeles University Foundation Medical Center

Background: Gestational Diabetes Mellitus (GDM) is a common condition that complicates a substantial number of pregnancies. Currently, the first line management for patients with GDM is dietary modification and exercise. Recent evidence suggest that there may be a complimentary hypoglycemic effect of substances such as vinegar.

Objectives: This study is a randomized, crossover trial, aiming to determine the effect of 2-week bedtime ingestion of apple cider vinegar (ACV) on the blood glucose concentration of gravidas diagnosed with GDM in a tertiary hospital. Specifically, it aims to describe the patients’ general profile, to determine the effect of ACV on the 75 grams OGTT levels of the subjects, to correlate the change in blood glucose levels with ingestion of the same amount of ACV with the patient’s BMI, and to determine the acceptability of ACV ingestion in pregnant patients.

Methods: There were 32 patients included in the study. Upon diagnosis of GDM, subjects were randomized into two groups. Group A had a sequence of Medical Nutrition Therapy (MNT) for 2 weeks followed by MNT plus ingestion of 2 tablespoons of ACV diluted in a cup of water for another 2 weeks. Group B had the reverse sequence. A 75g OGTT was taken on Day 0, Day 14, and Day 28 of treatment, in which the values were compared. The data were analyzed using SPSS 16.0.

Results: Results showed that there is a marginally significant increase in the fasting blood sugar (FBS) and 2nd hour blood sugar at the moment when ACV was withdrawn. A greater reduction in the blood sugar level was noted in patients with higher BMI during the period when patients were given the ACV. The Likert scale response was also done showing that ACV is acceptable, affordable and well-tolerated among pregnant patients.