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Case report: Rosai-Dorfman disease: pelvic manifestation

Joanna Marie M. Alday, MD and Antonio C. Cortez, MD, FPOGS, FPSUOG
Department of Obstetrics and Gynecology, San Juan de Dios Educational Foundation, Inc. Hospital

This is a case of a 51-year-old, Filipino, multipara, presenting with a five-month history of gradually enlarging pelvoabdominal mass. Initially assessed with multiple myoma, a total abdominal hysterectomy with bilateral salpingooophorectomy and excision of pelvic mass were done. Histopathology report of the mass showed Rosai-Dorfman Disease (RDD) and immunohistochemical stains, CD68 and S100, were both confirmatory. RDD within the pelvic cavity is an extremely rare occurrence with only seven reported cases globally on a wide-literature search. This paper describes the clinical presentation, imaging, management and histopathology of the case. The objective is to increase awareness on the pelvic manifestation of RDD and to provide health care professionals with additional knowledge for diagnosis and management of similar cases.

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